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Analysis of Placental Gene Expression Profile i...
53,40 € *
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Molecular biology of the placenta is a fascinating research subject to investigate the mechanisms underlying fetal growth abnormalities and developmental disorders. Analysis of Placental Gene Expression Profile in Abnormal Fetal Growth provides a new insight into the gene dysregulation and pathway changes in the placenta of pregnancies affected by fetal growth restriction and macrosomia. This book reviews the physiology of the placenta and its divers roles in maintaining a healthy fetal development. There is a summary of the aetiology of abnormal fetal growth and its adverse effects on the future of infants. The main focus of this book is presenting the findings achieved by microarray gene expression analysis in the placentas collected from growth restricted and macrosomic newborns, introducing some candidate genes for screening purposes. In addition, molecular function of dysregulated genes and affected biological pathways have been described in detail.

Anbieter: Dodax AT
Stand: 20.01.2020
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Chromosomal Instability in Cancer Cells
79,98 € *
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This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. The chromosomal basis for these aberrations is either translocations, which change the integrity of genes, or abnormal numbers of chromosomes, a condition referred to as aneuploidy, which results in abnormal gene expression levels. Such structural or numerical chromosomal aberrations are specific for distinct tumor entities. The degree of chromosomal instability and the degree of intratumor heterogeneity have profound consequences for disease outcome and for therapeutic stratification.

Anbieter: Dodax AT
Stand: 20.01.2020
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Chromosomal Instability in Cancer Cells
79,98 € *
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This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. The chromosomal basis for these aberrations is either translocations, which change the integrity of genes, or abnormal numbers of chromosomes, a condition referred to as aneuploidy, which results in abnormal gene expression levels. Such structural or numerical chromosomal aberrations are specific for distinct tumor entities. The degree of chromosomal instability and the degree of intratumor heterogeneity have profound consequences for disease outcome and for therapeutic stratification.

Anbieter: Dodax
Stand: 20.01.2020
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Assessment of Cancer-Related Fatigue on the Liv...
37,00 € *
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Cancer-related fatigue is a debilitating, multi-faceted biopsychosocial symptom experienced by the cancer survivors, begins after diagnosis and persists long after treatments end, even when the cancer is in remission. The etiological pathopsychophysiology underlying CRF is multifactorial, dysregulation of the homeostatic status of cytokines, irregularities in neuromuscular function, abnormal gene expression, inadequate ATP synthesis, serotonin dysregulation, abnormal vagal afferent nerve activation, an array of psychosocial mechanisms, including self-efficacy, causal attributions, expectancy, coping, and social support. An important first step in the management of CRF is the identification and treatment of associated comorbidities: anemia, hypothyroidism, pain, emotional distress, insomnia, malnutrition, and other comorbid conditions. Clinical management of these conditions will not necessarily alleviate CRF for a significant proportion of cancer survivors, intervention with additional therapeutic modalities may be required. The NCCN guidelines recommend that integrative nonpharmacologic behavioral interventions be implemented for the effective management of CRF.

Anbieter: Dodax AT
Stand: 20.01.2020
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Assessment of Cancer-Related Fatigue on the Liv...
35,90 € *
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Cancer-related fatigue is a debilitating, multi-faceted biopsychosocial symptom experienced by the cancer survivors, begins after diagnosis and persists long after treatments end, even when the cancer is in remission. The etiological pathopsychophysiology underlying CRF is multifactorial, dysregulation of the homeostatic status of cytokines, irregularities in neuromuscular function, abnormal gene expression, inadequate ATP synthesis, serotonin dysregulation, abnormal vagal afferent nerve activation, an array of psychosocial mechanisms, including self-efficacy, causal attributions, expectancy, coping, and social support. An important first step in the management of CRF is the identification and treatment of associated comorbidities: anemia, hypothyroidism, pain, emotional distress, insomnia, malnutrition, and other comorbid conditions. Clinical management of these conditions will not necessarily alleviate CRF for a significant proportion of cancer survivors, intervention with additional therapeutic modalities may be required. The NCCN guidelines recommend that integrative nonpharmacologic behavioral interventions be implemented for the effective management of CRF.

Anbieter: Dodax
Stand: 20.01.2020
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Sabri, A: Analysis of Placental Gene Expression...
51,90 € *
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Erscheinungsdatum: 01.06.2014, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Analysis of Placental Gene Expression Profile in Abnormal Fetal Growth, Autor: Sabri, Amin, Verlag: LAP Lambert Academic Publishing, Sprache: Englisch, Rubrik: Genetik // Gentechnologie, Seiten: 168, Informationen: Paperback, Gewicht: 272 gr, Verkäufer: averdo

Anbieter: averdo
Stand: 20.01.2020
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Cancerous Micronuclei
35,00 € *
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Theodor Boveri originally observed the fact that abnormal nuclear morphologies commonly occurred in cancer. Micronuclei are also referred to Howell-Jolly bodies, founded by hematologists William Henry Howell and Justin Marie Jolly in erythrocytes. Micronuclei induction by a chemical was first reported in Ehrlich ascites tumor cells treated with colchicine. The affect of environmental stressors on the expression of micronuclei was first analyzed in root tip cells under ionizing radiation.

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Stand: 20.01.2020
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Cancerous Micronuclei
34,00 € *
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Theodor Boveri originally observed the fact that abnormal nuclear morphologies commonly occurred in cancer. Micronuclei are also referred to Howell-Jolly bodies, founded by hematologists William Henry Howell and Justin Marie Jolly in erythrocytes. Micronuclei induction by a chemical was first reported in Ehrlich ascites tumor cells treated with colchicine. The affect of environmental stressors on the expression of micronuclei was first analyzed in root tip cells under ionizing radiation.

Anbieter: Dodax
Stand: 20.01.2020
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Epigenetic Therapy
49,00 € *
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Epigenetic is heritable changes in gene expression that do not involve changes in DNA sequence,is known to be involved in disease. Two important epigenetic changes that are known to contribute to disease are abnormal methylation patterns of DNA and modifications of histones in chromatin.This therapy describes a new development in pharmacology,epigenetic therapy,which attempts to correct these changes.

Anbieter: Dodax
Stand: 20.01.2020
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